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NAD+
An essential coenzyme found in every living cell, crucial for many biological processes. It plays a central role in metabolism, energy production, and cellular signaling. The body's natural NAD+ levels decline with age, and many chronic conditions are linked to this decrease. This has led to growing interest in NAD+ supplementation as a way to promote healthy aging.
Key functions of NAD+
Metabolism and energy production: NAD+ is vital for converting food into energy. It serves as a shuttle, accepting electrons (becoming NADH) from metabolic pathways like glycolysis and the Krebs cycle, and then donating those electrons to the electron transport chain to generate ATP.
- DNA repair and genomic stability: NAD+ is a required cofactor for enzymes called PARPs, which detect and repair DNA damage. Maintaining adequate NAD+ is critical for safeguarding the integrity of your genetic material as you age.
- Epigenetic regulation: NAD+ is a key cofactor for sirtuin enzymes, which regulate gene expression and silence genes associated with aging. Sirtuins are believed to play a protective role in age-related diseases.
- Cellular signaling: NAD+ facilitates communication between the cell's nucleus and mitochondria. This communication helps regulate vital processes like circadian rhythm, immune responses, and calcium balance.
- Neurological health: NAD+ is involved in synaptic plasticity and neuronal stress resistance. Studies suggest it may help counteract processes involved in neurodegenerative diseases.
NAD+ and aging
Scientific research has linked the natural decline of NAD+ levels with aging and numerous related diseases. By replenishing NAD+ levels, researchers hope to improve metabolic health and potentially extend an individual's "healthspan"—the length of time they live free from disease. Preclinical animal studies have shown that increasing NAD+ can mitigate some age-associated conditions, such as metabolic dysfunction and vision loss.
Disclaimer: This product is for research purposes only and is not intended for human consumption. By purchasing this product, the customer acknowledges and agrees to be a qualified researcher or professional who is using this product for strictly research, development, or educational purposes.
